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CHEMISTRY EDUCATION:
RESEARCH AND PRACTICE IN EUROPE
2002, Vol. 3, No. 2, pp. 229-252		 Theme Issue 2 on Structural Concepts
CONTRIBUTION FROM SCIENCE
(INVITED REVIEW PAPER)
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Ioannis P. GEROTHANASSIS, 1 Anastassios TROGANIS, 2
Vassiliki EXARCHOU, 1 and Klimentini BARBAROSSOU 1
1 University of Ioannina, Department of Chemistry
2 University of Ioannina, Department of Biological Applications and Technologies

NUCLEAR MAGNETIC RESONANCE (NMR) SPECTROSCOPY: BASIC PRINCIPLES AND PHENOMENA, AND THEIR APPLICATIONS
TO CHEMISTRY, BIOLOGY AND MEDICINE

ABSTRACT: Nuclear Magnetic Resonance (NMR) spectroscopy has made a tremendous impact in many areas of chemistry, biology and medicine. In this report a student-oriented approach is presented, which enhances the ability of students to comprehend the basic concepts of NMR spectroscopy and the NMR spectra of various nuclei. The origin of chemical shifts, coupling constants, spin relaxation and the Nuclear Overhauser Effect (NOE) will be discussed and their relation to molecular structure will be provided. A wide range of applications of NMR spectroscopy is presented, including exchange phenomena, the identification and structural studies of complex biomolecules, such as proteins, applications to food analysis, clinical studies, NMR as a microscope and magnetic tomography. [Chem. Educ. Res. Pract. Eur., 2002, 3, 229-252]

KEY WORDS: NMR spectroscopy; nuclear magnetic moment; screening constant; coupling constant; nuclear Overhauser effect (NOE); nuclear relaxation; applications of NMR

CORRESPONDENCE: (a) Ioannis P. GEROTHANASSIS, Department of Chemistry, Section of Organic Chemistry & Biochemistry, University of Ioannina, Ioannina, GR-45110, Greece; fax: +30 6510 98799; e-mail: igeroth@cc.uoi.gr;
(b) Anastassios TROGANIS, Department of Biological Applications and Technologies, University of Ioannina, Ioannina, GR-45110, Greece; fax: +30 6510 97064; e-mail: atrogani@cc.uoi.gr.

 

 

 

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